“A trip well worth taking, eye-opening and even mind-blowing.”
—Kirkus Reviews

Dear Readers,It’s been a while since I’ve written, but I have been busy reporting and writing a new book that I’ve just completed. I’m excited to tell you about it.

HOW TO CHANGE YOUR MIND: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence will be published in May. As the title suggests, the new book represents something of a departure for me—at least from writing about food.(As one early review put it, I’ve turned from “feeding your body to feeding your head.”)But as those of you who have been following my work for a while know, what unifies all my writing is a fascination with our symbiotic relationships with other species in nature, whether for food, beauty, or intoxication. I’ve had a long-standing interest in psychoactive plants and the age-old human desire to change the texture of consciousness. You may recall I wrote about cannabis inThe Botany of Desire and about growing opium in Harper’s several years before that.

The new book grew out of the reporting I did for a 2015 article about psychedelic psychotherapy in the New Yorker, called “The Trip Treatment.” I interviewed a number of cancer patients who, in the course of a single guided session on psilocybin (the main psychoactive molecule in magic mushrooms), had such a powerful mystical experience that their fear of death either faded or vanished altogether. I became curious to learn how that might be possible—how a molecule produced by a mushroom, of all things, could produce such a radical change in the mind of a human, such that death lost its sting.

So began what became a two-year journey into the world of psychedelics—LSD, psilocybin, Ayahuasca and something called 5-MeO-DMT. The book explores the renaissance of scientific research into these compounds and their potential to relieve several kinds of mental suffering, including depression, anxiety, and addiction. I spent time with neuroscientists who are using psychedelics in conjunction with modern brain imaging technologies to probe the mysteries of consciousness and the self. Several of the scientists I met are convinced psychedelics could revolutionize mental healthcare and our understanding of the mind.

But what I didn’t expect when I embarked on this journey was for it to result in what is surely the most personal book I’ve ever written. As you know, I like to immerse myself in whatever I’m writing—whether that means buying a steer or apprenticing myself to a baker. What began as a third-person journalistic inquiry ended up a first-person quest to learn what these medicines had to teach me about not only the mind but also my mind, and specifically about the nature of spiritual experience. This book has taken me places I’ve never been—indeed, places I didn’t know existed.

As you can imagine, I’m both excited and nervous to publish How to Change Your Mind this spring. I do hope you’ll check it out. I plan to post an excerpt on my website in a couple of months, and will alert you when I do. I’ll soon be updating the website with a rich array of resources on psychedelics. For now, though, here’s the advance review of the book from Kirkus, quoted from above.

I’ll be in touch more regularly in the next few months, to bring you news of the book as well as my extensive speaking schedule this spring. Hope to see you in person at one of these events.